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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) in complex with Cephalexin - Streptococcus pneumoniae R6

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Protein Data Bank Japan2026-04-01 更新2026-04-19 收录
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https://pdbj.org/mine/summary/9ssg
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) in complex with Cephalexin - Streptococcus pneumoniae R6 Descriptor: (2~{R})-2-[(1~{R})-1-[[(2~{R})-2-azanyl-2-phenyl-ethanoyl]amino]-2-oxidanylidene-ethyl]-5-methyl-5,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, Penicillin-binding protein 1B, ... Authors: Flanders, P.L, Gillingham, J.R, Contreras-Martel, C, Dessen, A, Carlson, E.E, Ambrose, E.A. Deposit date: 2025-09-25 Release date: 2026-02-18 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (1.642 Å) Cite: Structural and Dynamics Analyses of beta-Lactam Inhibition of Streptococcus pneumoniae Penicillin-Binding Protein 1b (PBP1b) Guide Interrogation of Structure-Activity Relationships. Acs Chem.Biol., 21, 2026
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2025-09-25
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