The contact lens dry eyes questionnaire (CLDEQ-8) validation and ocular surface dysfunction among soft contact lens wearers

ABSTRACT Purpose: To translate and validate the Contact Lens Dry Eyes Questionnaire (CLDEQ-8) to Portuguese language and to describe the impact of soft contact lenses on the ocular surface. Methods: We conducted a descriptive transversal study with the aim to: (1) translate and validate the CLDEQ-8 questionnaire to Portuguese language and (2) apply the CLDEQ-8 to a group of contact lens wearers along with a broad evaluation of the impact of soft contact lens on the ocular surface. The evaluation of the impact of soft contact lens was performed for a study population of 81 subjects, categorized in two groups: Group A: 61 contact lens wearers and Group B (control): 20 noncontact lens wearers. The study exclusion criteria were rigid contact lens wear, systemic or ocular diseases, the use of medications predisposing to ocular surface damage, and previous ocular surgeries. Results: For the CLDEQ-8 questionnaire translation and validation, Kappa agreement values were ³0.7 in all questions, implying a good agreement between the Portuguese and English language versions. Considering the ocular surface evaluation of the subjects, all parameters differed in Soft contact lens wearers when compared with the controls (p<0.05), except in those related to tear volume, such as the tear meniscus height and Schirmer test. Conclusions: This study provided a translated and validated Portuguese version of CLDEQ-8 questionnaire, which represents an important tool for the evolution of contact lens wearers. The broad evaluation of the ocular surface revealed an association between soft contact lens wearing and ocular surface disturbances.

摘要
研究目的：将角膜接触镜干眼问卷（Contact Lens Dry Eyes Questionnaire, CLDEQ-8）翻译成葡萄牙语并完成效度验证，同时描述软性角膜接触镜对眼表的影响。
研究方法：本研究为描述性横断面研究，旨在实现两大目标：(1) 将CLDEQ-8问卷翻译成葡萄牙语并进行效度验证；(2) 向一组角膜接触镜佩戴者施测CLDEQ-8问卷，并全面评估软性角膜接触镜对眼表的影响。本研究共纳入81名受试者，分为两组：A组为61名软性角膜接触镜佩戴者，B组（对照组）为20名非接触镜佩戴者。本研究的排除标准包括：硬性角膜接触镜佩戴史、全身性或眼部疾病、使用可能诱发眼表损伤的药物，以及既往眼部手术史。
研究结果：针对CLDEQ-8问卷的翻译与效度验证结果显示，所有条目Kappa一致性系数均≥0.7，表明葡萄牙语版本与英语版本之间具有良好的一致性。对受试者眼表的评估结果显示，软性角膜接触镜佩戴者的各项眼表参数与对照组相比均存在显著差异（p<0.05），但与泪液量相关的指标除外，包括泪河高度与Schirmer试验。
研究结论：本研究成功完成了CLDEQ-8问卷的葡萄牙语翻译与效度验证，该版本可作为评估角膜接触镜佩戴者眼部状况的重要工具。本次全面的眼表评估结果表明，软性角膜接触镜佩戴与眼表功能异常存在关联。