TOP1
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=733198
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资源简介：
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
该基因编码一种DNA拓扑异构酶，一种调控并改变转录过程中DNA拓扑状态的酶。此酶催化DNA单链的暂时断裂与重新连接，使得单链得以相互穿过，从而改变DNA的拓扑结构。该基因定位于第20号染色体上，并存在位于第1号和第22号染色体上的假基因。[由RefSeq提供，2008年7月]
提供机构：
Rat Genome Database
