cute effect of a moderate-intensity aerobic exercise session in the morning vs evening on glucose regulation, energy metabolism and molecular adaptations in skeletal muscle; role of sex: a randomized crossover study

Mammalian cells possess molecular clocks which adequate functioning is decisive for metabolic health. Exercise is known to modulate these clocks, potentially having distinct effects on metabolism depending on the time of day. Using a randomized crossover design, this study investigated the impact of morning vs. evening moderate-intensity aerobic exercise on glucose regulation (continuous glucose monitoring) and energy metabolism in healthy men and women. It also aimed to elucidate molecular mechanisms within skeletal muscle.