Computational Validation of a Clinical Decision Support Algorithm for Long-Acting Injectable PrEP Bridge Period Navigation at UNAIDS Global Target Scale

Clinical decision support tool validated at UNAIDS global scale (21.2M patients) for LAI-PrEP bridge period navigation. Provides population-specific risk stratification, barrier identification, and evidence-based intervention recommendations. Demonstrates 81.6% improvement in bridge period success (4.1M additional transitions globally). 100% unit test pass rate. Open-source Python implementation with external JSON configuration enabling local adaptation.