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Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3

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NIAID Data Ecosystem2026-05-26 收录
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In 3D cultures of hPSC-derived lung progenitors withdrawal of the GSK3 inhibitor, CHIR99021, induces multilineage maturation, including of proximal cells, type I alveolar epithelial cells and morphologically mature type II cells. Overall design: Lung Progenitors and D50 differentiated cells mRNA profiles were generated by deep sequencing, in triplicate, using Illumina HiSeq2500. D50 differentiated lung progenitor single-cell RNA profiles were generated using HiSeq4000 and 10x genomics' cellranger pipeline v2.0.0.

创建时间:
2019-02-04
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