Transcriptional profiling of mouse Th17 cells treated with bacterial metabolites 3-oxo-lithocholic acid [3-oxoLCA] and isolithocholic acid [isoLCA]
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
We report transcriptional profiling of mouse Th17 cells activated and expanded in vitro in the presence of Th17-inhibitory bacterial metabolites 3-oxoLCA and isoLCA. Naïve CD4 T cells from C57BL/6J mice were activated and expanded in Th17 polarization condition for 3 days in vitro. 3-OxoLCA and isoLCA were added 18 hours after T cell receptor (TCR) activation by anti-CD3 and anti-CD28 antibodies.
创建时间：
2022-04-01
