Additional file 3 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation

Additional file3: Table S2. Comparison of histone marks between sex and XCI status. See additional files. The first sheet shows BH adjusted p-values comparing female vs male and escape genes vs those subject to XCI per mark in CEMT with our meta-status and Xi/Xa expression based XCI status calls, along with CREST data with meta-status calls and CEMT data at enhancers with meta-status calls of linked genes. T-tests comparing Xi:Xa ratio per XCI status per dataset are shown on the right. The 2nd sheet shows the median value per mark with each sex and XCI status on the left and on the right shows the Xi/Xa ratio and log2 fold change per mark calculated based off of that median.

补充文件3：附表S2。不同性别与X染色体失活（X-chromosome inactivation, XCI）状态间的组蛋白修饰（histone marks）差异比较，详见其余补充文件。第一个工作表展示了经BH校正的P值，用于在CEMT数据集中，基于我们的元状态及Xi/Xa表达量的XCI状态判定结果，比较不同组蛋白修饰标记下雌性与雄性、逃逸XCI基因与受XCI调控基因间的差异；同时包含基于元状态判定结果的CREST数据集数据，以及调控关联基因增强子区域的CEMT数据集数据。右侧展示了按各数据集、各XCI状态分组的Xi:Xa比值的t检验结果。第二个工作表左侧展示了按不同性别与XCI状态分组的各标记的中位数值；右侧则展示了基于该中位数值计算得到的各标记的Xi/Xa比值与log₂倍变化值。