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PCSK9 in complex with an inhibitor
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2025-04-30
相关数据集
Dataset related to the article "Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis"
This record contains raw data related to the article "Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis" ABSTRACT The authors investigated whether PCSK9 inhibition could
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PCSK9(deltaCRD) in complex with cyclic peptide 83
PCSK9(deltaCRD) in complex with cyclic peptide 83 Descriptor: GLYCEROL, Peptide 83, Proprotein convertase subtilisin/kexin type 9 Authors: Orth, P. Deposit date: 2020-06-19 Release date: 2020-11-18 La
Protein Data Bank Japan2024-07-10 更新70
Potent Lys Patch-Containing Stapled Peptides Targeting PCSK9
Proprotein convertase subtilisin/kexin type 9 (PCSK9), identified as a regulator of low-density lipoprotein receptor (LDLR), plays a major role in cardiovascular diseases (CVD). Recently, Pep2-8, a sm
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Lipid parameters in different patient populations before and during (12 weeks) of therapy with PCSK9 inhibitors.
Lipid parameters in different patient populations before and during (12 weeks) of therapy with PCSK9 inhibitors.
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Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents
The optimization of a new class of small molecule PCSK9 mRNA translation inhibitors is described. The potency, physicochemical properties, and off-target pharmacology associated with the hit compound
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