Comprehensive gene expression analysis using microarray in TMD8 xenograft model.

The microarray data were normalized to the 75th percentile signal intensity as recommended by Agilent. Welch’s t-test of log-converted expression values was performed to find significant differentially expressed genes between the tirabrutinib and vehicle groups. Fold changes, nominal P-values and q-values of the differentially expressed genes are shown. Benjamini-Hochberg method was used as the correction method for the q-value. Geometric means of expression values for the tirabrutinib and vehicle groups are also shown. (XLSX)