Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 15c
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Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 15c Descriptor: RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{H}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide Authors: Landel, I, Mueller, M.P, Rauh, D. Deposit date: 2019-07-15 Release date: 2019-10-16 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity. Angew.Chem.Int.Ed.Engl., 58, 2019
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2019-07-15
