Correlation between GTEx and GWAS Z-scores of eQTLs from HLA-DQB1, HLA-DQA2 and HLA-DRB6.

Z-scores were calculated from T2D GWAS and GTEx (version 8) summary statistics for all the eQTLs for the three genes. Pearson correlation coefficient was calculated, and scatter plots were generated for eQTL data from five different tissues. Most of the TG lowering variants increases the expression of HLA-DQA2/HLA-DRB6, whereas decreases the expression of HLA-DQB1. (ZIP)