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Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming II

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP150764
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We collected duplicate samples at the various time points, generated single cell suspensions and performed scRNA-Seq. We also collected samples from established iPSC lines reprogrammed from the same MEFs, maintained in either 2i or serum conditions. Overall, we profiled ~250,000 cells. Overall design: We collected scRNA-seq profiles of 250,00 cells across a 18-day time course of iPSC induction, under two conditions: 2i and serum
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2025-05-31
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