IFIT2 CLIP-Seq to identify RNAs bound during influenza virus infection or IFNb treatment. Homo sapiens

This project sought to define the function of IFIT2 by identifying the RNAs it binds. IFIT2 expression was stimulated from the endogenous locus in human A549 (lung) cells during influenza virus infection or treatment with interferon-beta. A modified eCLIP procedure was used to identify IFIT2-bound RNAs. Data include IFIT2-bound RNA fragments as well as size-matched input controls. Experiments were repeated with independent biological duplicates.