High-Throughput Synthesis and Evaluation of Antiviral Copolymers to Target Enveloped Viruses

This dataset includes characterisation data for copolymers synthesised by high throughput PET-RAFT photopolymerisation strategy, including NMR and SEC analysis of polymers, and raw results from immunoplaque and cytotoxicity assays used to evaluate antiviral activity. Polymer association with models of viral membranes by Langmuir lipid monolayers are also included. Python scripts used for analysis of data set are included as a Jupyter Notebook.

New antiviral polymers to deactivate eneveloped viruses were synthesised and evaluated by a high-throughput experimental workflow.

本数据集涵盖通过高通量光致电子转移可逆加成断裂链转移（PET-RAFT）光聚合策略合成的共聚物的表征数据，包括聚合物的核磁共振波谱(NMR)与尺寸排阻色谱(SEC)分析结果，以及用于评估抗病毒活性的免疫斑试验与细胞毒性试验原始数据。此外还收录了通过朗缪尔脂质单分子层实验获取的、关于聚合物与病毒膜模型结合作用的相关数据。用于本数据集分析的Python脚本以Jupyter笔记本的形式一并提供。

本研究通过高通量实验流程合成并评估了可灭活有包膜病毒的新型抗病毒聚合物。