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Transcriptome profiling using microarrays of four human metformin-treated non-small cell lung cancer cell-lines

ChEBI2020-02-29 更新2026-07-12 收录

癌症药物转录组学

非小细胞肺癌细胞实验

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8781 数据链接链接失效反馈

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资源简介：

Transcriptome profiling using microarrays of four human metformin-treated non-small cell lung cancer cell-lines

应用场景：

创建时间：

2020-02-29

癌症药物转录组学

多发性骨髓瘤分子机制

The transcriptional profile of the human multiple myeloma (MM) cell line MM.1S treated with MLN4924 vs control MM.1S cells was characterized by oligonucleotide microarray analysis, using the human U13

NIAID Data Ecosystem90

Effect of metformin on mRNA expression in lung cancer cells. Effect of metformin on mRNA expression in lung cancer cells

癌症药物转录组学

细胞信号分析

The genes whose transcription was significantly altered by metformin were investigated in H1299 cells by RNA-seq. Significantly up- or down-regulated genes were identified by cutoff value of |FC| >= 1

NIAID Data Ecosystem20

Gene expression signatures of AMG510-treated pancreatic cancer cells and parental cells at transcriptomic level.

癌症药物转录组学

胰腺癌药物响应

To decipher the regulation patterns of these transporter or enzyme genes at the transcription level, we also treated MiaPaCa2 cells with DMSO or AMG510 at EC20 dosage for 120 minutes then performed RN

NIAID Data Ecosystem10

Celecoxib induced transcriptional alterations in gastric cancer cells

癌症药物转录组学

癌症信号通路

Celecoxib is recognized to have chemopreventive and anti-cancer property beyond its anti-inflammatory function. Celelcoxib treatment in AGS cells down regulates Wnt/β-catenin, STAT3, RXR and ERK/MAPK

NIAID Data Ecosystem60

BRBseq performed on 786-O cells treated with 2 inhibitors of protein kinase CK2, CX4945 and AB668. BRBseq performed on 786-O cells treated with 2 inhibitors of protein kinase CK2, CX4945 and AB668

癌症药物转录组学

CK2抑制剂作用机制

786-O cells (150, 000) were treated for 24h with DMSO, 5 µM of CX4945 or AB668. Total RNA was extracted from treated cells using the MirVana PARIS kit (Thermofisher). The 3′ Bulk RNA Barcoding and seq

NIAID Data Ecosystem10

Transcriptome profiling using microarrays of four human metformin-treated non-small cell lung cancer cell-lines

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