Crystal Structure of EcTS W80G/dUMP/CB3717 Complex
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Crystal Structure of EcTS W80G/dUMP/CB3717 Complex Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase Authors: Fritz, T.A, Liu, L, Finer-Moore, J.S, Stroud, R.M. Deposit date: 2002-02-06 Release date: 2002-07-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access. Biochemistry, 41, 2002
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2002-02-06
