Supplementary Material for: Risk Factors of Sexual Dysfunction in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study

<b><i>Background:</i></b> Hidradenitis suppurativa (HS) has a high impact on quality of life. However, sexual health has scarcely been investigated. <b><i>Objective:</i></b> To describe the frequency of sexual dysfunction (SD) in women and erectile dysfunction (ED) in men with HS and to explore potential risk factors. <b><i>Patients and Methods:</i></b><i></i>We conducted a cross-sectional study using a crowd-sourced online questionnaire spread by the Spanish hidradenitis suppurativa patients’ association (ASENDHI). <b><i>Results:</i></b> In total, 393 participants answered the questionnaire. SD was found in 51% (95% CI 45–57%) of women and ED in 60% (95% CI 49–70%) of men. Factors related to SD were education status, patient’s global assessment for disease activity, numeric rating scale for pain and unpleasant odour and the absence of a stable relationship. Factors related to ED were increasing age, the presence of active lesions in the genital area and the number of areas affected by active lesions. <b><i>Conclusions:</i></b> There is a high prevalence of SD and ED in HS patients. Being in a stable relationship has been a protective factor of SD in women. The results suggest that sexual impairment in HS patients is due, at least in part, to disease activity, symptoms and active lesions.

研究背景：化脓性汗腺炎（Hidradenitis suppurativa, HS）对患者的生活质量存在显著负面影响，但目前针对该疾病患者性健康的相关研究仍较为匮乏。
研究目的：明确化脓性汗腺炎患者中女性性功能障碍（sexual dysfunction, SD）与男性勃起功能障碍（erectile dysfunction, ED）的患病率，并探索潜在的危险因素。
研究对象与方法：本研究依托西班牙化脓性汗腺炎患者协会（ASENDHI）发布的众包线上问卷，开展了一项横断面调研。
研究结果：总计393名参与者完成了本次问卷调研。女性群体中性功能障碍（SD）的患病率为51%（95%置信区间：45%~57%），男性群体中勃起功能障碍（ED）的患病率为60%（95%置信区间：49%~70%）。与女性性功能障碍相关的影响因素包括受教育程度、患者对疾病活动度的整体评估、疼痛与异味的数字评分量表评分，以及无稳定伴侣关系。与男性勃起功能障碍相关的影响因素包括年龄增长、生殖器部位存在活动性皮损，以及受累皮损的区域数量。
研究结论：化脓性汗腺炎患者群体中性功能障碍与勃起功能障碍的患病率均处于较高水平。拥有稳定伴侣关系是女性发生性功能障碍的保护因素。本研究结果提示，化脓性汗腺炎患者的性功能损害至少部分源于疾病活动度、临床症状及活动性皮损。