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Methylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies

ChEBI2008-06-15 更新2026-07-21 收录

肿瘤甲基化标记物

小细胞肺癌表观遗传学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-6695 数据链接链接失效反馈

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资源简介：

Methylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies

应用场景：

创建时间：

2008-06-15

小细胞肺癌表观遗传学

突变负荷分析

: Table S1. Clinical characteristics of 89 NSCLCs in this study. Table S2. The post-alignment QC metrics information of WES. The post-alignment QC metrics information of WES including expected depth,

NIAID Data Ecosystem110

Propionate reinforces epithelial identity and reduces aggressiveness of non-small cell lung carcinoma via chromatin remodelling [RNA-seq]

小细胞肺癌表观遗传学

RNA测序基因表达分析

To investigate the effect of sodium propionate (SP) in enhancing the epithelial gene program in NSCLC, lung cancer cells were treated with SP at different time points. Gene expression profiling using

NIAID Data Ecosystem60

Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition and tumorigenesis of non-small cell lung cancer. Homo sapiens

小细胞肺癌表观遗传学

组蛋白修饰

Histone acetylation is associated with active transcription in eukaryotic cells. It helps to open up the chromatin by neutralizing the positive charge of histone lysine residues, and by providing bind

NIAID Data Ecosystem30

Additional file 6 of ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer

小细胞肺癌表观遗传学

增强子调控

Additional file 6: Table S5. Super enhancers that are co-occupied by both ASXL3 and BRD4.

Figshare2020-07-16 更新90

Genome-wide maps of chromatin state in K-RasLSL-G12D and K-RasLSL-G12D;Mll4fl/fl induced lung tumors in mice

小细胞肺癌表观遗传学

小鼠疾病模型

Here, we show that the histone H3 lysine (H3K4) methyltransferase MLL4 (a COMPASS/SET1-like enzyme; also called KMT2D) is ranked the most highly inactivated epigenetic modifier in NSCLC tumors lung-sp

NIAID Data Ecosystem40

Methylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies

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