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Human Genetics Influences Microbiome Composition Involved in Asthma Exacerbations despite Inhaled Corticosteroid Treatment

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NIAID Data Ecosystem2026-05-01 收录
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Additional Supplement Data of the manuscript Perez-Garcia J, Espuela-Ortiz A, Hernández-Pérez JM, et al. Human Genetics Influences Microbiome Composition Involved in Asthma Exacerbations despite Inhaled Corticosteroid Treatment (in press). J Allergy Clin Immunol. 2023;S0091-6749(23)00748-0. doi:10.1016/j.jaci.2023.05.021. This Supplement Data contains the following items: Additional Table 1 List of independent mbQTLs associated with p<1x10-5 in the mbGWAS from saliva samples in Europeans (discovery). Additional Table 2 List of independent mbQTLs associated with p<1x10-5 in the mbGWAS from pharyngeal samples in Europeans (discovery). Additional Table 3 List of independent mbQTLs associated with p<1x10-5 in the mbGWAS from nasal samples in Europeans (discovery). Additional Table 4 Summary results of enrichment analyses using the Enrichr platform. Additional Table 5 Summary results of stratified enrichment analyses by biological sample type. Additional Table 6 List of independent mbQTLs associated with p<1x10-5 in the mbGWAS from saliva samples in African Americans (replication phase). Additional Table 7 List of independent mbQTLs associated with p<1x10-5 in the mbGWAS from saliva samples in Latinos (replication phase). Additional Table 8 Summary results of replication enrichment analyses in saliva samples. Additional Table 9 Summary statistics of the mbQTL analysis of Streptococcus in nasal samples. Additional Table 10 Summary statistics of the mbQTL analysis of Campylobacter in pharyngeal samples. Additional Table 11 Summary statistics of the mbQTL analysis of Tannerella in pharyngeal samples. Additional Table 12 Summary table of the different genetic models tested for each mbQTL pair.
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2023-06-30
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