Additional file 3 of Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation

Additional file 3: Tab. S2. Differentially methylated CpGs in iPSCs versus iMSCs (WT or DNMT3A knockouts). CpG sites that are either 50% hypo- or hypermethylated in DNMT3A wildtype, exon 2-/-, exon 19-/-, or exon 23-/- iMSCs compared to their iPSC counterparts with associated genes, gene groups, relation to CpG islands, chromosomes, positions, mean beta-values of the knockout and wildtype cells, and the difference in methylation between knockout and wildtype.

附加文件3：附表S2。本附表收录了诱导多能干细胞（induced pluripotent stem cells, iPSCs）与诱导间充质干细胞（induced mesenchymal stem cells, iMSCs）间的差异甲基化CpG位点，样本包含野生型（wild type, WT）及DNA甲基转移酶3A（DNA methyltransferase 3A, DNMT3A）敲除的iMSCs。具体涵盖：相较于其对应iPSCs，在DNMT3A野生型、外显子2-/-、外显子19-/-及外显子23-/-的iMSCs中呈现50%低甲基化或高甲基化的CpG位点；附带关联信息包括相关基因、基因分组、与CpG岛的位置关系、所在染色体及基因组位置、敲除组与野生型细胞的平均β甲基化值，以及敲除组与野生型组之间的甲基化差异。