Gonioscopy-Assisted Transluminal Trabeculotomy: A Review

To review the recent evidence in the literature regarding the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in the management of pediatric and adult glaucoma. A literature search was performed in the electronic databases of PubMed, Google Scholar, Embase the Register of Controlled Trials, and Ovid Medline for studies evaluating the safety and outcomes of GATT in glaucoma. GATT is a novel minimally invasive glaucoma surgery that allows the incision of the inner wall of Schlemm’s canal increasing aqueous drainage through the physiologic outflow pathway with subsequent intraocular pressure reduction in different types if of glaucoma. GATT demonstrated favorable results in a wide range of both primary and secondary open-angle and angle-closure glaucoma.本研究旨在回顾当前文献中有关房角镜辅助经管小梁切开术（gonioscopy-assisted transluminal trabeculotomy, GATT）治疗儿童与成人青光眼的有效性及安全性证据。本研究通过检索PubMed、Google Scholar、Embase、临床试验注册库（Register of Controlled Trials）及Ovid Medline等电子数据库，筛选评估GATT治疗青光眼的安全性与临床结局的相关研究。GATT作为一种新型微创青光眼手术，可通过切开施莱姆管（Schlemm’s canal）内壁，经由生理性房水流出通路增加房水引流，进而降低各类青光眼患者的眼压。现有研究表明，GATT在各类原发性、继发性开角型及闭角型青光眼的治疗中均取得了良好效果。