Isolate properties by sequenced emm type.

Observed rates of antibiotic resistance and scarlet fever exotoxin gene carriage for all identified sequence-based emm types. N+(N) = Number of Positives (Number Tested). Bold indicates 50% or greater rates of resistance. Positives either carry a particular spe gene or show resistance to a particular antibiotic (inclusive of both intermediate and full resistance). ERY, erythromycin; CLI, clindamycin; TET, tetracycline; LEV, levofloxacin; CHL, chloramphenicol; OFX, ofloxacin. aIndependently significant specific association, positive or negative. bSignificant after alpha (Bonferroni) adjustment for multiple measures (highly significant). speA, scarlet fever exotoxin gene A; speC, scarlet fever exotoxin gene C. These following results are not shown in the table: 100% of tested isolates (in all cases N>300) were susceptible to penicillin (PEN), vancomycin (VAN), cefepime (CPM), cefotaxime (CTX), ceftriaxone (CTR), linizolid (LNZ), meropenem (MEM), and gatifloxacin (GAT). 311 were tested with quinupristin-dalfopristim (SYN) and one was resistant, six isolates were tested with trovafloxacin (TVA) and 3 were resistant.