Additional file 1 of Reproducibility of EEG functional connectivity in Alzheimer’s disease

Additional file 1: Supplementary Table 1. Difference in functional connectivity (FC) between SCD and AD subjects estimated by ANOVA model 1 (correction for age and gender). Supplementary Table 2. Difference in functional connectivity (FC) between SCD and AD subjects estimated by ANOVA model 2 (correction for age, gender and global relative power). Supplementary Figure S1. Topographical distribution of the median difference in Z-score of the PLI and AEC-c between the SCD and AD subjects. Supplementary Figure S2A & 2B. Summary of observed differences in ANOVA model 1, shown as effect size (Cohen’s d), between AD and SCD subjects in different regions for the AEC-c and PLI in each bandwidth. Supplementary Figure S3A-C. Correlation coefficients (r) between functional connectivity measures in the theta (A), alpha (B) and beta (C) bandwidths. In each figure, the coefficients on the right are corrected for changes in relative power and the coefficients on the left are the uncorrected values.

附加文件1：补充表1。基于方差分析（analysis of variance, ANOVA）模型1（校正年龄与性别）估算的主观认知下降（Subjective Cognitive Decline, SCD）与阿尔茨海默病（Alzheimer's Disease, AD）受试者间的功能连接（functional connectivity, FC）差异。补充表2。基于方差分析（ANOVA）模型2（校正年龄、性别及全局相对功率）估算的SCD与AD受试者的功能连接差异。补充图S1。SCD与AD受试者的相位滞后指数（Phase Lag Index, PLI）与校正振幅包络相关（Amplitude Envelope Correlation-corrected, AEC-c）的Z评分中位数差异的拓扑分布。补充图S2A与2B。各频段下，AEC-c与PLI在不同脑区的AD与SCD受试者间的ANOVA模型1观测差异汇总，以效应量（科恩d值，Cohen’s d）呈现。补充图S3A-C。θ（A）、α（B）及β（C）频段内功能连接指标间的相关系数（r）。各图中，右侧为校正相对功率变化后的相关系数，左侧为未校正的原始数值。