Single-cell transcriptomics of human intestinal organoids infected with SARS-CoV-2. Single-cell transcriptomics of human intestinal organoids infected with SARS-CoV-2

In this work we have employed a single cell sequencing approach of both ileum and colon organoids using 10x Genomics scRNAseq and TAP-seq targeted single-cell RNA-seq. Overall design: 10x Genomics single-cell RNA sequencing V3.1 and targeted single-cell RNA-seq (TAP) was perfomed on Colon and Ilean organoids infected with SARS-CoV-2 at mock condition and after 12hpi and 24hpi