Extended Data Figure 5 – Source Data (intrinsic and synaptic physiology in S1BF L2/3 neurons)

This dataset contains the raw numerical values used to generate Extended Data Figure 5, which examines intrinsic excitability and excitatory synaptic transmission in layer 2/3 pyramidal neurons of the S1BF following repeated ketamine administration.<br>Included data:- Intrinsic properties (Panels 5B–F), including resting membrane potential, input resistance, voltage sag, action potential firing rates in response to 0–400 pA current steps, and rheobase- Spontaneous EPSC frequency and amplitude from layer 2/3 neurons (Panels 5G–H)- Evoked EPSC responses during 10 Hz stimulation (Panels 5I–J), including normalized amplitudes and paired-pulse ratios- Release parameters estimated from 50 Hz, 100-stimulus trains (Panels 5K–L), including vesicle refilling rate and readily releasable pool (RRP) size<br>Structure:- The worksheet includes per-cell intrinsic measurements, sEPSC values, 10 Hz response amplitudes, paired-pulse ratios, and release parameter estimates for Ctrl and rKet groups.- These values correspond to the physiological data underlying Extended Data Figure 5.<br><br>