AK-2P

AK-2P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample AK-2P:<br>A: Denotes the control group.<br>K: Represents timepoint 3, indicating sampling after PBS.<br>2: Refers to the specific mouse number under investigation.<br>P: Indicates the treatment administered, which in this case is Lactobacillus paracasei.AK-2P 研究了副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。感染后小鼠的粪便样本经Invitrogen试剂处理后，在Ion Torrent NGS测序系统上完成测序。通过Ion Reporter SW（16S）开展分析后发现，在感染后第1、3、6天，微生物类群的动态变化特征显著，该研究揭示了益生菌在艰难梭菌感染期间调控肠道菌群的潜在应用价值。 样本AK-2P的含义说明如下： A：代表对照组； K：代表时间点3，即经磷酸盐缓冲液（PBS）处理后采样的时间节点； 2：指代本次研究中的受试小鼠专属编号； P：代表所施加的干预措施，本研究中为副干酪乳杆菌（Lactobacillus paracasei）。