Targeting Vdac2 overcomes immunotherapy resistance by inducing tumor cell death and inflammation [microarray 4]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261549
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Uncovered IFNg signal and mitochondrial stress shaping tumor immune evasion We treated B16-OVA-Cas9-sgNTC (indicated as WT), sgVdac2 (indicated as V2-KO), sgBak1 (indicated as Bak1-KO), sgApaf1 (indicated as Apaf1-KO), sgVdac2 + sgBak1 (indicated as Vdac2-Bak1-dKO) or sgVdac2 + sgApaf1 (indicated as Vdac2-Apaf1-dKO) tumor cells with IFNg, survived tumor cells were collected for RNA extraction and microarray analysis.
创建时间：
2025-06-18
