Electric_Bioimpedance_H&N_Dataset

The objective of the study is to prove the efficacy of the new Smartprobe system, which is based on Electrical Bioimpedance (EBI) sensing technology in the diagnosis of the head and neck squamous cell carcinoma. A prospective observational ex-vivo study was carried out analyzing 43 patients submitted to surgical procedures for head and neck squamous cell carcinoma (SCC) between May, 2019 and October, 2020. The Smartprobe system is composed by a laptop with a specific software connected to an electrode-needle to punch and analyze the EBI of ex vivo tissue. By measuring the variation of the phase (σ) and conductivity (θ), the device can distinguish healthy from pathologic tissue. The outcomes have been compared to the definitive histopathological di-agnosis as gold standard. For different tissue types, five classifiers were developed to analyze the accuracies of the methodic. The accuracy of these classifiers, on the testing set, was 74.52%, 88.37%, 76.19%, 72.81%, and 89.58% for mucosa, skin, muscle, lymph node and cartilage, respec-tively.The results of this study demonstrate that the SmartProbe technology is helpful in distin-guishing squamous cell carcinomas from healthy tissue in the mucosa, muscle, skin, and cartilage but not in the lymph nodes. This issue could be explained because of similarity of the electrical cellular characteristic between the lymphatic tissue and the hypercellularity of the SCC tissue, particularly when relatively low frequencies are used for their assessment.本研究旨在验证基于生物电阻抗（Electrical Bioimpedance, EBI）传感技术的新型Smartprobe系统在头颈部鳞状细胞癌诊断中的应用效能。本研究为一项前瞻性观察离体研究，共纳入2019年5月至2020年10月期间43例接受头颈部鳞状细胞癌（head and neck squamous cell carcinoma, SCC）外科手术的患者。Smartprobe系统由搭载专用软件的笔记本电脑与电极针组成，可完成离体组织的穿刺操作并检测其生物电阻抗。通过分析相位（σ）与导电率（θ）的变化，该设备能够区分健康组织与病变组织。本研究以最终组织病理学诊断作为金标准，对检测结果进行对照验证。针对不同组织类型，研究构建了五种分类器以评估该检测方法的诊断准确率。在测试集上，五种分类器针对黏膜、皮肤、肌肉、淋巴结及软骨的诊断准确率分别为74.52%、88.37%、76.19%、72.81%及89.58%。本研究结果显示，SmartProbe技术可有效区分黏膜、肌肉、皮肤及软骨组织中的鳞状细胞癌与健康组织，但无法鉴别淋巴结组织中的病变与正常组织。该现象可归因于淋巴组织与鳞状细胞癌组织的高细胞性在电学细胞特性上的相似性，尤其当采用较低频率进行检测时，这一局限更为突出。

搜集汇总

背景与挑战

背景概述

该数据集聚焦于头颈鳞状细胞癌诊断，通过电阻抗生物传感技术（Smartprobe系统）分析离体组织，旨在区分健康与病理组织。它包含43名患者的数据，涵盖黏膜、皮肤、肌肉、淋巴结和软骨等多种组织类型，分类器测试准确率介于72.81%至89.58%之间，但淋巴结区分效果有限，体现了技术在临床应用中的潜力和局限性。