Area compressibility modulus (KA) data for: Effects of Lipid Headgroups on the Mechanical Properties and In Vitro Cellular Internalization of Liposomes

Area compressibility modulus (KA) of DOPC-based lipid bilayers mixed with the saturated lipids DSPG, DSPA, DSPS, DSPC and DSPE (5–35 mol%), determined from all-atom molecular dynamics simulations at 298.15 K using four surface tensions. Each row gives the bilayer composition, KA (mN/m) with its reported uncertainty, the % difference relative to pure DOPC, and the t-score and p-value of a two-sample t-test against pure DOPC (n1 = n2 = 4, df = 6, critical t = 2.447). Larger systems used for corroboration are flagged. Data correspond to Table S2 of the Supporting Information of Xu et al., Langmuir (2025), DOI 10.1021/acs.langmuir.4c04363. Provided as an Excel workbook (with a README sheet defining all columns) and an equivalent UTF-8 CSV.