Dicer conditional knockout embryonic heart mutant vs control array

The goal is to find out the gene expression changes when Dicer was inactivated in the murine heart. Keywords: Dicer mutant Dicer gene was specifically inactivated in the mouse heart using cardiac specific Nkx2.5 Cre knock-in line. Embryonic day 11.5 heart from mutant and control hearts were compared in triplicates.本研究旨在探究小鼠心脏内Dicer灭活时的基因表达变化情况。 关键词：Dicer突变体 本研究采用心脏特异性Nkx2.5 Cre敲入系，对小鼠心脏内的Dicer基因进行特异性灭活。分别取突变型与对照小鼠的胚胎第11.5天心脏组织，以三份平行样本开展对比实验。