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Neuroblastoma Disease Pathogenesis is Modulated By Epigenetically Regulated MicroRNAs

ChEBI2012-10-16 更新2026-07-21 收录

神经母细胞瘤致病机制

表观遗传-microRNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-3498 数据链接链接失效反馈

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Neuroblastoma Disease Pathogenesis is Modulated By Epigenetically Regulated MicroRNAs

应用场景：

创建时间：

2012-10-16

神经母细胞瘤致病机制

环状RNA功能研究

Neuroblastoma (NB), a malignant embryonic tumor arising from primitive neural crest cells, accounts for more than 7% of malignancies and around 15% of cancer-related mortality in childhood. Better elu

NIAID Data Ecosystem20

LIN28B Regulates Transcription and Potentiates MYCN-induced Neuroblastoma in a let-7-independent Manner [RNA-seq]

神经母细胞瘤致病机制

转录调控

LIN28B is highly expressed in neuroblastoma and promotes tumorigenesis at least in part through inhibition of let-7 microRNA biogenesis. Here, we report that overexpression of either wild-type LIN28B,

NIAID Data Ecosystem00

The Kinesin KIF1BÃ links neuroblastoma and neurodegenerative disease through anterograde transport of TRKA

神经母细胞瘤致病机制

KIF1B基因功能研究

We recently identified pathogenic KIF1Bb mutations in sympathetic nervous system malignancies that are defective in developmental apoptosis. Here we deleted KIF1Bb in the mouse sympathetic nervous sys

NIAID Data Ecosystem00

Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models

神经母细胞瘤致病机制

交感神经元分化模型

Heterozygous germline mutations and deletions in PHOX2B, a key regulator of autonomic neuron development, predispose to neuroblastoma, a tumor of the peripheral sympathetic nervous system. To gain ins

Figshare2016-01-18 更新00

Neuroblastoma Disease Pathogenesis is Modulated By Epigenetically Regulated MicroRNAs

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