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A Concise Approach to Paxilline Indole Diterpenes

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https://figshare.com/articles/dataset/A_Concise_Approach_to_Paxilline_Indole_Diterpenes/2098792
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资源简介:
A synthetic approach to paxilline indole diterpenes is described. The route to the penta­cyclic core relies on a new regio­selective alkenyl­ation of ketones and a tandem radical addition–aldol reaction sequence to access vicinal quaternary stereo­centers. Emindole SB, the simplest member of the family, is synthesized in 11 steps from commercially available material to demonstrate the application of this approach.
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2016-02-12
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