Agmatine treatment enhanced functional outcome following compression SCI.

The BMS score was used to evaluate hindlimb locomotor function. The BMS scores in the Agm treated mice (Agm treated group, n = 30) were significantly higher than the saline treated mice (EC group, n = 30) at 1, 3, 7, 10, 14, 21, 28 and 35 DPI. The Bladder residual urine volumes were measured in Agm treated group (n = 10) and in the EC group (n = 10). The graph showed that the amount of residual urine was significantly decreased in the Agm treated group compared with the EC group until 14 DPI. *, p<0.05 EC group vs Agm treated group. Results represent mean ± S.E.M.