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Crystal structure of EHMT2 SET domain in complex with compound 13

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of EHMT2 SET domain in complex with compound 13 Descriptor: Histone-lysine N-methyltransferase EHMT2, N2-[4-methoxy-3-(2,3,4,7-tetrahydro-1H-azepin-5-yl)phenyl]-N4,6-dimethyl-pyrimidine-2,4-diamine, S-ADENOSYLMETHIONINE, ... Authors: Suzuki, M, Mizuno, M, Katayama, K. Deposit date: 2020-04-06 Release date: 2020-11-11 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines. Bioorg.Med.Chem.Lett., 30, 2020
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2020-04-06
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