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Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase Descriptor: 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Senkovich, O, Schormann, N, Chattopadhyay, D. Deposit date: 2006-05-19 Release date: 2008-04-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
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2006-05-19
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