Comparative analysis of host transcriptomic responses induced by exoU, exoU mutant and exoS Pseudomonas aeruginosa in a murine keratitis model

This dataset contains transcriptomic data from a murine scarification model of Pseudomonas aeruginosa keratitis comparing a wild-type (WT) exoU strain, its exoU-deleted mutant, and an exoS strain at 48 h post-infection. RNA sequencing was performed on infected BALB/c mouse corneas to identify host transcriptional responses associated with exoU-driven corneal disease. This dataset contains 17 files organised into three categories: DEG files (5), KEGG enrichment files (7), GO enrichment files (4). All DEG files contain complete gene lists including genes highlighted in the paper.All KEGG files contain complete enrichment results; figures in the paper display the top 20 pathways as a representative subset.All GO files contain complete enrichment results; figures in the paper display second-level GO classification histograms showing the number of differentially expressed genes per GO category (biological process, molecular function, and cellular component).