Quaternary Complex of human dihydroorotate dehydrogenase (DHODH) with flavin mononucleotide (FMN), orotic acid and AG-636
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Quaternary Complex of human dihydroorotate dehydrogenase (DHODH) with flavin mononucleotide (FMN), orotic acid and AG-636 Descriptor: 1-methyl-5-(2'-methyl[1,1'-biphenyl]-4-yl)-1H-benzotriazole-7-carboxylic acid, ACETATE ION, CHLORIDE ION, ... Authors: Padyana, A, Jin, L. Deposit date: 2020-01-29 Release date: 2020-11-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase. Mol.Cancer Ther., 19, 2020
创建时间：
2020-01-29
