The METTL3 RNA methyltransferase regulates androgen signalling in castrate resistant prostate cancer cells
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP356710
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资源简介：
siRNAs targeting METTL3 used to deplete METTL3 in castrate resistant LNCaP:C42 and 22Rv1 prosate cancer cells and the effect on basal and androgen regulated gene expression and splicing determined. Overall design: A pool of siRNAs were used to deplete METTL3 in castrate resistant but enzalutamide sensitive LNCaP:C42 and enzalutamide-resistant 22Rv1 prostate cancer cells and the effect on basal and androgen (R1881, 1nM) regulated gene expression and alternative splicing determined using RNA sequencing.
创建时间：
2025-08-08
