Transcriptomic analysis of the intestine of Urechis unicinctus infected with Vibrio anguillarum

Vibrio anguillarum is one of the common pathogenic bacteria in aquaculture. In order to investigate the changes of host gene expression level and the molecular mechanism of response to bacterial infection after V. anguillarum infected marine economic animal-Urechis unicinctus, the high-throughput sequencing technology was adopted to sequence the transcriptomes of intestine of different groups of U. unicinctus after infected with V. anguillarum, including control group, susceptibility group and disease-resistance group, and then the differently expressed genes(DEGs) and signal channels were comparative analyzed in this study. This study may provide data referenced for further exploring the mechanism of infection against aquaculture animals by V. anguillarum and the immune response of U. unicinctus to pathogenic bacteria.