Seroprotection rate, seroconversion rate, and HAI GMT of 46 subjects at day 28 after vaccination.

Data presented as mean ± standard deviation or number (percentage).a: Mc'Nemar exact test for the change of response over time.b: Comparison between Seroconversion rate and immunogenicity criteria of Committee for Proprietary Medicinal Products (CPMP) was analyzed by Binomial Exact test.c: Wilcoxon signed rank test for the change of HAI titer over time.*: statistically significant (pNA, not applicable.