EFFECTS OF DIETARY SODIUM MONENSIN ON THE METABOLIC AND HORMONAL PROFILES OF DAIRY GOATS DURING THE PERIPARTUM PERIOD

Abstract This study aimed to investigate the energetic and hormonal profiles of dairy goats fed diets supplemented with monensin during the peripartum period. Eleven pregnant Saanen goats were subdivided into two random groups, a control group (GC) and the monensin group (MG). The MG group received 40 mg sodium monensin per animal per day for 15 days before partum and throughout the subsequent experimental period. Clinical observations and sample collection were performed at 30, 15, and 7 days before birth; on the day of partum; and at 5, 15, and 30 days after birth. The following biochemical and hormonal profile variables analyzed were: cholesterol, triglycerides, glucose, fructosamine, non-esterified fatty acids (NEFAs) and β-hydroxybutyrate (BHB), cortisol, and insulin. The ruminal fluid pH, chloride content, and volatile fatty acids were also measured. Statistical analysis of the data was performed using repeated measures ANOVA (p < 0.05) and Pearson's correlation. At partum, the MG group had lower values of NEFAs and lower acetate/propionate ratio. MG had higher triglycerides during the entire experiment period. The administration of monensin generated benefits in terms of energy parameters, improving the metabolic status of the dairy goats during peripartum.

摘要：本研究旨在探究围产期饲喂添加莫能菌素（monensin）日粮的萨能奶山羊的能量与激素代谢特征。选取11头妊娠萨能奶山羊，随机分为对照组（GC）与莫能菌素组（MG）。莫能菌素组每只羊每日饲喂40 mg莫能菌素钠（sodium monensin），于产前15天开始给药，并持续至整个后续实验周期。分别于产前30、15、7天、分娩当日以及产后5、15、30天开展临床观察与样本采集。本次分析的生化与激素代谢指标包括：胆固醇、甘油三酯、葡萄糖、果糖胺、非酯化脂肪酸（non-esterified fatty acids，NEFAs）、β-羟丁酸（β-hydroxybutyrate，BHB）、皮质醇与胰岛素。此外还检测了瘤胃液（ruminal fluid）pH值、氯离子含量与挥发性脂肪酸（volatile fatty acids）。数据统计分析采用重复测量方差分析（repeated measures ANOVA，p<0.05）与皮尔逊相关分析（Pearson's correlation）。结果显示，分娩当日，莫能菌素组的非酯化脂肪酸与乙酸/丙酸比值均显著降低；整个实验周期内，莫能菌素组的甘油三酯水平均显著升高。饲喂莫能菌素可改善能量代谢相关指标，提升围产期奶山羊的代谢健康状态。