Additional file 8: of First gene-ontology enrichment analysis based on bacterial coregenome variants: insights into adaptations of Salmonella serovars to mammalian- and avian-hosts

Candidates of PAI-like region overlapping genomic islands (cPAIs) impacted by intragenic and non-homoplastic variants (SNPs and InDels) fixed in Salmonella enterica subsp. enterica serovars Dublin versus all the others genomes (Ontology 1 called ‘Dub_All’), Pullorum/Gallinarum versus Enteritidis (Ontology 2 called ‘Ent_Pull/Gall’), Pullorum versus Gallinarum (Ontology 3 called ‘Pull_Gall’), and Gallinarum versus Pullorum (Ontology 4 called ‘Gall_Pull’). Pathogenicity Island Database from KonKuk University (Seoul, South Korea) were used to detect Salmonella Pathogenic Islands (SPIs) SPI-1 (2890501–2,934,879), SPI-2 (1727425–1,769,273), SPI-4 (4333507–4,361,514), SPI-5 (1053174–1,074,167), SPI-6 (299796–330,890), SPI-11 (1904313–1,912,607), SPI-12 (2328077–2,347,757) and PAI III 536 (2801306–2,810,695) of the reference genome S. Enteritidis (strain P125109, accession NC_011294.1). (XLSX 251 kb)

本数据集包含与基因组岛（genomic island）重叠的类致病性岛区域候选序列（cPAIs），此类序列受基因内变异与非同源变异（单核苷酸多态性SNPs与插入缺失InDels）影响，上述变异已在以下四组比较基因组中固定：1. 本体1（命名为"Dub_All"）：肠炎沙门氏菌肠炎亚种都柏林血清型与其余所有基因组的比较组；2. 本体2（命名为"Ent_Pull/Gall"）：鸡白痢/鸡伤寒血清型与肠炎血清型的比较组；3. 本体3（命名为"Pull_Gall"）：鸡白痢血清型与鸡伤寒血清型的比较组；4. 本体4（命名为"Gall_Pull"）：鸡伤寒血清型与鸡白痢血清型的比较组。本研究采用韩国首尔建国大学的致病性岛数据库（Pathogenicity Island Database），对参考基因组肠炎沙门氏菌P125109菌株（登录号NC_011294.1）的沙门氏菌致病性岛（Salmonella Pathogenic Islands，SPIs）进行检测，所覆盖的致病性岛区域包括：SPI-1（2890501–2,934,879）、SPI-2（1727425–1,769,273）、SPI-4（4333507–4,361,514）、SPI-5（1053174–1,074,167）、SPI-6（299796–330,890）、SPI-11（1904313–1,912,607）、SPI-12（2328077–2,347,757）以及PAI III 536（2801306–2,810,695）。本数据集文件格式为XLSX，大小为251 kb。