five

Mus musculus strain:Balb/c | breed:Inbred Transcriptome or Gene expression

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP584804
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This project investigates the role of lymphatic endothelial cells (LECs) in regulating immune responses during autoimmune myocarditis. Using a mouse model of experimental autoimmune myocarditis (EAM) induced by cardiac myosin peptide in BALB/c mice, we examined the effects of vascular endothelial growth factor-C (VEGF-C) on cardiac inflammation. Mice were treated with VEGF-C C156S, a selective VEGFR3 agonist, to stimulate lymphangiogenesis during peak inflammation. The data include RNA-seq profiles from VEGF-C- and PBS-treated hearts, providing insight into lymphatic-endothelial mediated immune regulation.
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2025-05-15
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