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Genetically defined human GBM organoids reveal principles of GBM development and actionable targets

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213835
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We used single cell RNA sequencing (scRNA-seq) to analysis the cellular state of organoids harboring different genetic mutations scRNA-sequencing data for 1- and 4-month-old WT (wildtype), PT (PTEN-/-; TP53-/-), PTCC (PTEN-/-; TP53-/-; CDKN2A-/-; CDKN2B-/-), and PTN (PTEN-/-; TP53-/-; NF1-/-) organoids samples
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2024-01-27
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