Divergent Stereocontrol of Acid Catalyzed Intramolecular Aldol Reactions of 2,3,7-Triketoesters: Synthesis of Highly Functionalized Cyclopentanones
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https://figshare.com/articles/dataset/Divergent_Stereocontrol_of_Acid_Catalyzed_Intramolecular_Aldol_Reactions_of_2_3_7_Triketoesters_Synthesis_of_Highly_Functionalized_Cyclopentanones/2503531
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资源简介：
The intramolecular acid catalyzed aldol cyclization of 2,3,7-triketoesters formed from ζ-keto-α-diazo-β-ketoesters provides highly functionalized cyclopentanones with good diastereoselectivity in high overall yields via kinetically controlled and stereodivergent catalytic processes. Lewis acid catalysis gives high selectivity for the 1,2-anti tetrasubstituted cyclopentanones, whereas Brønsted acid catalysis produces the corresponding 1,2-syn diastereomer.
创建时间：
2016-02-20
