five

Impact of anti-CD40 treatment on mouse livers

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE159761
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Treating samples with anti-CD40, and antibiotics to establish what transcriptional impact antibiotics is having. Anti-CD40 was found to induce a strong inflammatory signature. Antibiotics in combination with anti-CD40 attenuated this resulting in a much improved phenotype. However the detectable transcriptional differences were somewhat modest. 20 samples in total. 5 per group. 4 groups, which are Control. Contorl + ABX. Anti-CD40, Anti-CD40 + ABX. All are from individual mice. No longitudinal measurements.
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2022-01-24
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