Ruthenium-Catalyzed Enantioselective Hydrogenation of 1,8-Naphthyridine Derivatives
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https://figshare.com/articles/dataset/Ruthenium-Catalyzed_Enantioselective_Hydrogenation_of_1_8-Naphthyridine_Derivatives/3394030
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资源简介：
The first asymmetric
hydrogenation of 2,7-disubstituted 1,8-naphthyridines
catalyzed by chiral cationic ruthenium diamine complexes has been
developed. A wide range of 1,8-naphthyridine derivatives were effectively
hydrogenated to give 1,2,3,4-tetrahydro-1,8-naphthyridines with up
to 99% ee and full conversions. The method provides a practical and
facile approach to the preparation of valuable chiral heterocyclic
building blocks and useful motifs for a new kind of P,N-ligand.
创建时间：
2016-05-27
