Effect of osteocytes mitochondria on OA chondrocytes

To investigate the regulatory role of MLO-Y4 mitochondria on OA chondrocytes, we isolated mitochondria from MLO-Y4 and transplanted to chondrocytes treated with IL-1ß. We then performed gene expression profiling analysis using data obtained from RNA-seq of chondrocytes from vehicle group and mitochondria transplanted group. Overall design: Comparative gene expression profiling analysis of RNA-seq data for OA chondrocytes and OA chondrocytes transplanted with mitochondria.