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Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cell types of origin

ChEBI2017-12-19 更新2026-07-12 收录

癌症表观遗传学

肿瘤分子分型

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-5738 数据链接链接失效反馈

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Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cell types of origin

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创建时间：

2017-12-19

癌症表观遗传学

甲基化测序

We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec

Figshare2016-01-19 更新70

Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Mapping Context-Aware Phosphosite Regulation of Protein–Protein Interactions Using Deep Learning and Pan-Cancer Proteomics

磷酸化位点调控蛋白互作预测

癌症表观遗传学

Phosphorylation dynamically orchestrates the protein–protein interaction (PPI) network that governs cellular signaling, and its dysregulation frequently drives malignant transformation and neurodegene

NIAID Data Ecosystem30

Additional file 4 of Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

癌症表观遗传学

肿瘤化疗敏感性预测

Additional file 4: Table S4. Significant strong trans- and cis-correlations of GMD expression with methylation of individual probes in the pancancer dataset satisfying p 0.5.

Figshare2021-03-06 更新60

Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice

前列腺癌模型

肿瘤分子分型

Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) in

NIAID Data Ecosystem40

Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cell types of origin

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